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J Neural Transm (Vienna). 2009 Dec;116(12):1607-11. doi: 10.1007/s00702-009-0310-1. Epub 2009 Sep 22.

Upper gastrointestinal findings in Huntington's disease: patients suffer but do not complain.

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Department of Neurology, Huntington-Center NRW, St. Josef Hospital, Gudrunstrasse 56, 44791 Bochum, Germany.


We investigated, retrospectively, the prevalence of gastroesophageal inflammation in patients with Huntington's disease (HD) during 10 years in our center. We found a high prevalence of gastritis or esophagitis even in patients without complaints, indicating that gastrointestinal disease is more common in HD than patients' complaints. There was no correlation with motor disturbances but with the duration and severity of HD. Influences from the disease itself as well as secondary mechanisms like malnutrition, medication and general disability may contribute.

[Indexed for MEDLINE]

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