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Am J Obstet Gynecol. 2010 Jan;202(1):71.e1-6. doi: 10.1016/j.ajog.2009.07.042. Epub 2009 Sep 20.

Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus, and polyomavirus are not detectable in human tissue with epithelial ovarian cancer, borderline tumor, or benign conditions.

Author information

1
Department of Clinical Science/Obstetrics and Gynecology, Umeå University, Sweden.

Abstract

OBJECTIVE:

We sought to analyze the presence of the microorganisms Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus (HPV), and the polyomaviruses BK virus (BKV) and JC virus (JCV) in ovarian tissues of women with ovarian carcinomas, borderline tumors, and benign conditions.

STUDY DESIGN:

Ovarian tissue, snap-frozen and stored at -80 degrees C, from 186 women with benign conditions, borderline tumors, and epithelial ovarian cancer, as well as tissue from the contralateral ovary of 126 of these women, were analyzed regarding presence of C trachomatis and N gonorrhoeae (transcription mediated amplification), M genitalium (real-time polymerase chain reaction [PCR]), HPV (PCR), and BKV and JCV (PCR).

RESULTS:

All the tissue samples studied were found negative for the microorganisms analyzed.

CONCLUSION:

C trachomatis, M genitalium, N gonorrhoeae, HPV, and the polyomaviruses BKV and JCV are not detectable in ovarian tissues either from women with benign conditions and borderline tumors or from women with ovarian cancer.

PMID:
19766974
DOI:
10.1016/j.ajog.2009.07.042
[Indexed for MEDLINE]

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