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Cell. 2009 Sep 18;138(6):1062-4. doi: 10.1016/j.cell.2009.09.001.

Reducing the mystery of neuronal differentiation.

Author information

1
Department of Neurobiology, Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. bnovitch@ucla.edu

Abstract

In the developing nervous system, neural progenitors exit the cell cycle and differentiate on a precise schedule, yet the mechanisms driving this process remain poorly defined. Yan et al. (2009) now identify a thiol-redox reaction mediated by the membrane protein GDE2 and the peroxiredoxin protein Prdx1 that promotes neurogenesis.

PMID:
19766560
DOI:
10.1016/j.cell.2009.09.001
[Indexed for MEDLINE]
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