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Clin Pharmacol Ther. 2009 Oct;86(4):360-2. doi: 10.1038/clpt.2009.133.

Predicting age-specific dosing of antipsychotics.

Author information

1
Centre for Addiction and Mental Health, Geriatric Mental Health Program, Ontario, Canada.

Abstract

Antipsychotic medications are the standard of care for both acute and maintenance treatment of schizophrenia, the latter requiring an indefinite treatment across a patient's life span. However, dosing and tolerability of antipsychotics have been studied primarily in younger patients, and very limited data are available for age- and phase-specific dosing. This leaves the clinician with no guidance on dose adjustment as patients grow older-an issue of critical importance, especially in light of recent concerns about increased morbidity and mortality associated with antipsychotics.

PMID:
19763115
DOI:
10.1038/clpt.2009.133
[Indexed for MEDLINE]

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