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Nucleic Acids Res. 2009 Nov;37(20):6643-54. doi: 10.1093/nar/gkp698. Epub 2009 Sep 17.

FIGfams: yet another set of protein families.

Author information

1
Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, USA. folker@anl.gov

Abstract

We present FIGfams, a new collection of over 100,000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried out, ensuring a previously unattained degree of throughput and consistency. FIGfams are based on over 950,000 manually annotated proteins and across many hundred Bacteria and Archaea. Associated with each FIGfam is a two-tiered, rapid, accurate decision procedure to determine family membership for new proteins. FIGfams are freely available under an open source license. These can be downloaded at ftp://ftp.theseed.org/FIGfams/. The web site for FIGfams is http://www.theseed.org/wiki/FIGfams/.

PMID:
19762480
PMCID:
PMC2777423
DOI:
10.1093/nar/gkp698
[Indexed for MEDLINE]
Free PMC Article

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