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Lancet. 1990 Sep 29;336(8718):765-8.

Jejunal efflux in short bowel syndrome.

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1
St Mark's Hospital, London, UK.

Abstract

24 h oral intake and intestinal output were studied in 15 patients with a short residual length of jejunum and no colon. 8 patients showed a net secretory, and 7 a net absorptive response to food. In secretors, daily intestinal output exceeded oral intake (mean 2.3 kg wet weight, and 233 mmol sodium). Long-term parenteral fluid and electrolyte replacements were needed only in those with a secretory response. Jejunal length inversely correlated with net intestinal output of fluid, sodium, potassium, and with percentage energy absorption. A secretory response was observed if jejunal length was less than 100 cm and was reduced by gastric antisecretory drugs and octreotide.

PMID:
1976145
DOI:
10.1016/0140-6736(90)93238-k
[Indexed for MEDLINE]

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