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Zhen Ci Yan Jiu. 2009 Jun;34(3):180-2, 187.

[Effect of electroacupuncture of "Neiguan" (PC 6) on heart rate and plasma catecholamine contents in ventricular tachycardia rats].

[Article in Chinese]

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Department of Acu-moxibustion and Osteo-traumatology, Hubei College of Chinese Medicine, Wuhan 430061, China.



To observe the effect of electroacupuncture (EA) of "Neiguan" (PC 6) on heart rate (HR) and plasma catecholamine (CA) levels in ventricular tachycardia (VT) rats.


A total of 50 SD rats were randomly divided into normal control, sham-operation (sham), model, EA-PC 6 and EA-LU 7 groups, with 10 cases in each. VT model was established by intravenous injection of cesium chloride (CsCl) via femoral vein. Electrocardiogram (ECG) was recorded. EA (2 Hz/15 Hz, 1 mA) was separately applied to bilateral "Neiguan" (PC 6) and "Lieque" (LU 7) for 5 minutes, followed by collecting blood samples for detecting plasma norepinephrine (NE) and epinephrine (E) levels with fluorometric method.


In comparison with normal control group, plasma NE and E contents in model group increased apparently (P < 0.01). Compared with model group, HR and plasma NE and E contents of EA-PC 6 group reduced significantly (P < 0.01), while those of EA-LU 7 had no apparent change (P > 0.05).


EA of "Neiguan" (PC 6) can downregulate heart rate and plasma CA level in VT rats, which may contribute to its effect in relieving tachycardia.

[Indexed for MEDLINE]

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