Send to

Choose Destination
J Infect Dev Ctries. 2009 Apr 30;3(3):218-20.

Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya.

Author information

Department of Medical Microbiology, Medical School, University of Al-Marghib, Al-Kums, Libya.



Human parvovirus B19 has been implicated as a primary etiologic agent of erythema infectiosum (fifth disease) and aplastic crisis in patients with chronic haemolytic anemias. Human parvovirus B19 is known to be associated with adverse effects on fetuses such as hydrops fetalis, intrauterine fetal death, and chronic anaemia in immunocompromized individuals. The objective of this study was to assess the seroprevalence of human parvovirus B19 among the pregnant women in Tripoli, Libya.


A total number of 150 participants were included in the study, consisting of women of child-bearing age ranging from 18 to 41 years, and divided into age groups as follows: < or = 21 years, 22-27, 28-32, 33-37, and > or = 38 years. Specific IgM and IgG antibodies were measured using a commercial ELISA kit.


IgG was observed to be prevalent (61%) among the women of child-bearing age. The sero-prevalence of IgM was found to be 5% overall and there was no detectable IgM in the age group between 33 and 37.


The presence of IgG and absence of IgM indicate immunity to primary infection, but a significant percentage of child-bearing aged women are at risk of primary infection with parvovirus B19 which could adversely affect their pregnancy.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for The Journal of Infection in Developing Countries
Loading ...
Support Center