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Urology. 2010 Feb;75(2):407-13. doi: 10.1016/j.urology.2009.05.050. Epub 2009 Sep 16.

Canary Prostate Active Surveillance Study: design of a multi-institutional active surveillance cohort and biorepository.

Author information

1
Department of Urology, University of Washington, Seattle, Washington 98195, USA.

Abstract

Active surveillance is a management plan for localized prostate cancer that offers selective delayed intervention on indication of disease progression, allowing patients to delay or avoid treatment and associated side-effects. Outcomes from centers that promote active surveillance are favorable, with high rates of disease-specific survival. However, there remains a need for prognostic variables or biomarkers that distinguish with high specificity the aggressive cancers that progress on surveillance from the indolent cancers. The Canary Prostate Active Surveillance Study is a multicenter study and a biorepository that will discover and confirm biomarkers of aggressive disease as defined by histologic, prostate-specific antigen, or clinical criteria.

PMID:
19758683
PMCID:
PMC3827723
DOI:
10.1016/j.urology.2009.05.050
[Indexed for MEDLINE]
Free PMC Article

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