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Dev Cell. 2009 Sep;17(3):307-9. doi: 10.1016/j.devcel.2009.08.015.

Mechanisms of cellular protrusions branch out.

Author information

1
Department of Cell Biology, Duke University Medical School, Durham, NC 27710, USA.

Abstract

F-BAR domains bind curved membranes and induce membrane invagination. In a recent Cell paper, Guerrier et al. describe an "inverse" F-BAR family member that induces outward curvature and filopodia in migrating neurons. These findings suggest that F-BAR domains are functionally diverse and regulate different types of membrane morphology.

PMID:
19758555
PMCID:
PMC4226656
DOI:
10.1016/j.devcel.2009.08.015
[Indexed for MEDLINE]
Free PMC Article

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