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Clin Ter. 2009;160(3):211-3.

[Proctological surgery: advantages derived from the use of an innovative detergent in the post-operative period].

[Article in Italian]

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Dipartimento di Chirurgia Generale e Trapianti d'Organo, Istituto 'Paride Stefanini', Università Sapienza, Roma, Italia.



This study was aimed to verify the efficacy, in terms of healing, reepithelization and discomfort, of a detergent cream to be locally used after surgery for the most frequent pathologies of anal canal and perineal region.


The study was carried out on a "presentation sample" of 40 patients, 30 with clinico-instrumental diagnosis of III-IV degree haemorrhoids, 10 with diagnosis of chronic anal fissures, provided by 5 Colonproctological Centers, who entered a clinical follow-up after colonproctological surgery for their respective pathologies. The tested detergent cream (Anonet liquid) is composed by natural substances, such as Aloe vera, Hamamelis, Calendule e Hippocastane, as the lenitive and antiinflammatory principles, and Elastine, as a stimulatory agent of dermal elastic fibers, plus zincus oxide that has a protective, reparative and lenitive action, rice's starch with an anti-inflammatory action, liver fish oil and potassium glicirizzinate with high lenitive and anti-inflammatory action. The product does not contain strong tensioactive substances as well as preservants. The patients were asked to apply the cream on the perianal and perineal region twice a day for at least 12 days after surgery.


The study demonstrated that in 84% of tested patients the prescribed cream has favoured the prevention of infective complications by stimulating a normal reepithelization, and diminished the anal discomfort related to burning and pruritus. The cream did not cause irritative and allergic manifestations, skin damage as well as pharmacological toxicity.


The post-surgical use of the tested detergent cream, composed by the above-cited active principles, is recommended for locally preventing the infections, promoting the reepithelization, minimizing the perineal discomfort in patients operated of haemorrhoids and anal fissures.

[Indexed for MEDLINE]

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