Format

Send to

Choose Destination
Biochem Soc Trans. 2009 Oct;37(Pt 5):961-5. doi: 10.1042/BST0370961.

How and why does the endoplasmic reticulum move?

Author information

1
Faculty of Life Sciences, University of Manchester, The Michael Smith Building, Oxford Road, Manchester, UK.

Abstract

The ER (endoplasmic reticulum) is a fascinating organelle that is highly dynamic, undergoing constant movement and reorganization. It has many key roles, including protein synthesis, folding and trafficking, calcium homoeostasis and lipid synthesis. It can expand in size when needed, and the balance between tubular and lamellar regions can be altered. The distribution and organization of the ER depends on both motile and static interactions with microtubules and the actin cytoskeleton. In the present paper, we review how the ER moves, and consider why this movement may be important for ER and cellular function.

PMID:
19754432
DOI:
10.1042/BST0370961
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center