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Cell Host Microbe. 2009 Sep 17;6(3):199-200. doi: 10.1016/j.chom.2009.08.007.

Shifting the paradigm: host gene signatures for diagnosis of infectious diseases.

Author information

1
Division of Pediatric Infectious Diseases, Nationwide Children's Hospital and the Ohio State University College of Medicine, Columbus, OH 43205, USA. octavio.ramilo@nationwidechildrens.org

Abstract

Instead of focusing on the pathogen, in a paradigm shift, Zaas et al. (2009) identified host gene profiles as a strategy for diagnosis of respiratory infections. Application of host gene profiles offers tremendous possibilities for identification of diagnostic signatures, markers of disease severity, and eventually, prognostic indicators in the clinical setting.

PMID:
19748461
DOI:
10.1016/j.chom.2009.08.007
[Indexed for MEDLINE]
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