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Res Microbiol. 2009 Nov;160(9):652-9. doi: 10.1016/j.resmic.2009.08.011. Epub 2009 Sep 8.

Degradation of cytoplasmic substrates by FtsH, a membrane-anchored protease with many talents.

Author information

1
Ruhr-Universität Bochum, Lehrstuhl für Biologie der Mikroorganismen, Bochum, Germany. franz.narberhaus@rub.de

Abstract

Control of cellular processes by regulated proteolysis is conserved among all organisms. FtsH, the only membrane-anchored AAA protease in bacteria, fulfills a variety of regulatory functions. This review focuses on soluble FtsH substrates in Escherichia coli and in other bacteria and outlines emerging substrate recognition principles.

PMID:
19744556
DOI:
10.1016/j.resmic.2009.08.011
[Indexed for MEDLINE]

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