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Rev Med Inst Mex Seguro Soc. 2009 Mar-Apr;47(2):179-84.

[Risk factors associated with upper gastrointestinal bleeding and with mortality].

[Article in Spanish]

Author information

1
Unidad de Investigación Médica, Instituto Mexicano del Seguro Social, Durango, Durango, Mexico.

Abstract

OBJECTIVE:

to determine the associated risk factors with upper gastrointestinal bleeding (UGIB) and mortality in subjects with peptic ulcer.

METHODS:

a total of 345 subjects with peptic ulcer, < 60 years of age, were enrolled in a cross-sectional study. Subjects were allocated into one of two groups in accordance with the presence of UGIB. A logistic regression model, adjusted by age and sex, was used to compute the relationship between the risk factors and both UGIB and mortality.

RESULTS:

smoking (OR = 2.6, CI 95 % = 1.2-8.7), alcohol consumption (OR = 4.8, CI 95 % = 1.4-10.5), and previous history of UGIB (OR = 1.8, CI 95 % = 1.1-9.7) were strongly and independently associated with UGIB; chronic obstructive pulmonary disease (OR = 1.9, CI 95 % = 1.2-11.4), and high blood pressure (OR = 1.4, CI 95 % = 1.1- 7.5) were associated with mortality in UGIB.

CONCLUSIONS:

the associated risk factors with UGIB in patients with peptic ulcer were: age lower than 60 years; smoking; history of UGIB; and alcohol consumption. The chronic obstructive pulmonary disease and high blood pressure were associated with mortality in UGIB.

PMID:
19744387
[Indexed for MEDLINE]

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