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Neurocase. 2009 Dec;15(6):515-26. doi: 10.1080/13554790903061371. Epub 2009 Sep 7.

Rest-activity and behavioral disruption in a patient with frontotemporal dementia.

Author information

1
University of California, San Francisco, Memory and Aging Center, 350 Parnassus Ave., San Francisco, CA 94019-1207, USA. jmerrilees@memory.ucsf.edu

Abstract

The neurological deterioration in dementia is associated with disturbances in circadian rhythms and rest-activity patterns. These disruptions have been documented in Alzheimer's disease (AD) and dementia with Lewy bodies but little is known about rest-activity patterns in patients with frontotemporal dementia (FTD). We report longitudinal (2 year) actigraphy results for a patient who met diagnostic criteria for FTD and his family caregiver. The subject and his family caregiver wore Actiwatches continuously for 2 weeks at 1-year intervals. The findings suggest that with disease progression there is worsening in multiple areas of rest-activity measures for the patient and a negative impact on sleep quality for the family caregiver.

PMID:
19736599
PMCID:
PMC2829101
DOI:
10.1080/13554790903061371
[Indexed for MEDLINE]
Free PMC Article

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