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J Pediatr Surg. 2009 Sep;44(9):1848-55. doi: 10.1016/j.jpedsurg.2009.04.037.

Use of angioembolization as an effective technique for the management of pediatric solid tumors.

Author information

1
Pediatric Surgery Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Spain. lkrauel@hsjdbcn.org

Abstract

PURPOSE:

In oncology practice, angioembolization has been reported for tumor reduction before surgery, treatment of life-threatening conditions, and for palliative care. Nevertheless, the overall experience with angioembolization for the treatment of tumors is limited. We report our experience in 7 nonvascular solid pediatric tumors.

MATERIALS AND METHODS:

A retrospective review was carried out of medical records from pediatric patients (0-18 years) with solid nonvascular tumors who underwent angioembolization in the last 5 years at our institution.

RESULTS:

Seven patients underwent embolization: 2 neuroblastomas, 1 metastatic paraganglioma, 1 hepatoblastoma, 1 myofibroblastic tumor, 1 osteosarcoma, and 1 undifferentiated sarcoma. The reason for angioembolization was preparation for surgery (3), treatment of a life-threatening event (1), or palliative care (3). Each case is presented and discussed. The outcome was subsequent complete surgical resection in 3 cases, tumor vanished in 1 case, symptom control was achieved in 1, and the other 2 patients improved their survival and quality of life, however, died of disease progression.

CONCLUSIONS:

Tumor angioembolization may enter the treatment algorithm for selected patients who have to face difficult or unwarranted surgical procedures or have diseases where conventional therapies have failed.

PMID:
19735840
DOI:
10.1016/j.jpedsurg.2009.04.037
[Indexed for MEDLINE]

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