Format

Send to

Choose Destination
World J Biol Psychiatry. 2009;10(4 Pt 2):626-8. doi: 10.1080/15622970903144004.

Beneficial effects of N-acetylcysteine in treatment resistant schizophrenia.

Author information

1
Department of Psychiatry, Gaziantep University Faculty of Medicine, Gaziantep, Turkey.

Abstract

Poor response to antipsychotics is still an important problem in the treatment of many schizophrenia patients. N-acetylcysteine (NAC) is a compound that exerts anti-oxidant and scavenging actions against reactive oxygen species. This paper reports a case of poorly responsive schizophrenia patient who improved considerably with add-on NAC 600 mg/day. The NAC might work through activating cysteine-glutamate antiporters or reducing in nitric oxide (NO) metabolites, free radicals and cytokines or through both of these mechanisms.

PMID:
19735056
DOI:
10.1080/15622970903144004
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center