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Biosci Biotechnol Biochem. 2009 Sep;73(9):2117-20. Epub 2009 Sep 7.

Dimethyl trisulfide as a characteristic odor associated with fungating cancer wounds.

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1
Department of Integrated Biosciences, The University of Tokyo, Chiba 277-8562, Japan.

Abstract

Some advanced cancer patients suffer from pungent sulfury malodor. To determine the chemical identity of the odorant, we performed gas chromatography-mass spectrometry-olfactometry analysis of volatiles from fungating cancer wounds. We identified the source of the characteristic smell as dimethyl trisulfide, a compound that is known to be emitted from some vegetables and microorganisms. Controlling the production of dimethyl trisulfide should improve quality of life of patients.

PMID:
19734656
DOI:
10.1271/bbb.90229
[Indexed for MEDLINE]
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