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J Neurol Sci. 2010 Feb 15;289(1-2):155-8. doi: 10.1016/j.jns.2009.08.030. Epub 2009 Sep 4.

Increased activation in cingulate cortex in conversion disorder: what does it mean?

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Department of Neurology, University Medical Center Groningen, University of Groningen, The Netherlands.


Conversion disorder is one of the terms used to describe various psychosomatic neurological symptoms that are thought to originate from a psychological conflict. Psychological stressors can usually be identified but appear to be almost similar to the severity of psychological stress in non-psychosomatic neurological disorders. Recent neuroimaging research provides one rather robust finding of increased activation in the anterior cingulate gyrus. This activation has been explained as a reflection of 'active inhibition' or 'self-monitoring' but its meaning in conversion disorder still remains mysterious. In this paper, current theories are re-examined from a neuroanatomical point of view.

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