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Blood Purif. 2009;28(4):359-63. doi: 10.1159/000235856. Epub 2009 Sep 1.

Mortality trends associated with acute renal failure requiring dialysis after CABG surgery in the United States.

Author information

1
Division of Cardiothoracic Anesthesiology and Critical Care Medicine, Department of Anesthesiology, Duke University Medical Center, Durham, N.C. 27710, USA.

Abstract

BACKGROUND/AIMS:

Acute renal failure is associated with a high risk of mortality when it complicates coronary artery bypass graft (CABG) surgery. We examined a large nationwide database from 1988 to 2003 and hypothesized that mortality in CABG-associated acute renal failure needing dialysis (ARF-D) had declined during this period.

METHODS:

The Nationwide Inpatient Sample containing data on inpatient stays across 20% of US hospitals was used for our study. Multivariate logistic regression was used to determine an association between year and ARF-D mortality with standardized risk adjustment.

RESULTS:

Incidence of ARF-D increased from 0.2 to 0.6% while mortality simultaneously decreased from 47.4% in 1988 to 29.7% in 2003. In the multivariable model, year was significantly associated with declining ARF-D mortality.

CONCLUSIONS:

The incidence of post-CABG ARF-D more than doubled from 1988 to 2003, while mortality simultaneously decreased by over one-third. Improved survival after ARF-D following CABG may be counterbalanced by increased morbidity and resource utilization.

PMID:
19729906
DOI:
10.1159/000235856
[Indexed for MEDLINE]

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