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J Asthma. 2009 Sep;46(7):699-702. doi: 10.1080/02770900903056195.

Serum vitamin A and beta-carotene levels in children with asthma.

Author information

1
Department of Biochemistry, College of Science, King Saud University, Saudi Arabia. senaidy@ksu.edu.sa

Abstract

BACKGROUND:

Low serum levels of dietary antioxidants are associated with allergic diseases including asthma. Vitamin A and carotenoids are dietary antioxidants that are likely to play an important role against airway inflammation.

METHODS:

This study included 433 asthmatic schoolchildren and 537 healthy control subjects, between 6 and 18 years of age. Serum beta-carotene, vitamin A, cholesterol, and triglycerides levels were studied in all subjects.

RESULTS:

Serum vitamin A concentration was significantly lower in asthmatic subjects than in healthy control subjects (19.4 +/- 1.1 mg/dL vs. 28.9 +/- 0.86 mg/dL) (p < 0.001). There were no significant differences in the levels of beta-carotene, cholesterol, and triglycerides between the two groups.

CONCLUSION:

Reduction of vitamin A in asthmatic children may have etiological implications for the disease.

PMID:
19728208
DOI:
10.1080/02770900903056195
[Indexed for MEDLINE]

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