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Opt Express. 2009 Aug 31;17(18):15659-69. doi: 10.1364/OE.17.015659.

Automated segmentation of the macula by optical coherence tomography.

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  • 1Optoelectronics and Measurement Techniques Laboratory, University of Oulu, 90014 University of Oulu, Finland.


This paper presents optical coherence tomography (OCT) signal intensity variation based segmentation algorithms for retinal layer identification. Its main ambition is to reduce the calculation time required by layer identification algorithms. Two algorithms, one for the identification of the internal limiting membrane (ILM) and the other for retinal pigment epithelium (RPE) identification are implemented to evaluate structural features of the retina. Using a 830 nm spectral domain OCT device, this paper demonstrates a segmentation method for the study of healthy and diseased eyes.

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