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Nat Cell Biol. 2009 Sep;11(9):1049-51. doi: 10.1038/ncb0909-1049.

RISC hitches onto endosome trafficking.

Abstract

The RNA-induced silencing complex (RISC) downregulates expression of the genes targeted by RNA-silencing pathways. But formation and turnover of the RISC complex itself is tightly regulated and requires endosomal membranes.

PMID:
19724258
DOI:
10.1038/ncb0909-1049
[Indexed for MEDLINE]
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