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Am J Crit Care. 2009 Sep;18(5):418-26; quiz 427. doi: 10.4037/ajcc2009473.

Surrogate consent for genomics research in intensive care.

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  • 1ITT-Technical Institute, St Louis, Missouri, USA.


Surrogate decision makers may be poorly prepared to give informed consent for genomics research for their loved ones in intensive care. A review of the challenges and strategies associated with obtaining surrogates' consent for genomics research in intensive care patients revealed that few well-controlled studies have been done on this topic. Yet, a major theme in the literature is the role of health care professionals in guiding surrogates through the informed consent process rather than simply witnessing a signature. Informed consent requires explicit strategies to approach potential surrogates effectively, educate them, and ensure that informed consent has been attained.

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