Format

Send to

Choose Destination
Am J Reprod Immunol. 2009 Oct;62(4):261-7. doi: 10.1111/j.1600-0897.2009.00734.x. Epub 2009 Aug 24.

Serum IL-6 level may have role in the pathophysiology of unexplained infertility.

Author information

1
Obstetrics and Gynecology Clinic, Health Ministry Ergani Goverment Hospital, Diyarbakir, Turkey. bulentdemirmd@hotmail.com

Abstract

PROBLEM:

The aim of this study was to compare the serum levels of interleukin (IL)-6 of women with unexplained infertility with fertile subjects.

METHOD OF STUDY:

Serum IL-6, and tumor necrosis factor-alpha (TNF-alpha) levels of 45 infertile and 44 fertile women on day 3 of menstrual cycle were assessed and compared for this prospective controlled study.

RESULTS:

The mean serum IL-6 level was significantly higher in women with unexplained infertility, compared with fertile women (5.71 +/- 1.81 and 4.31 +/- 1.79, P < 0.001, Student's t-test). There was no significant difference in TNF-alpha level among the groups.

CONCLUSION:

Significant difference in serum IL-6 levels between unexplained infertile and fertile women suggests that this cytokine may be involved in pathophysiology of unexplained infertility.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center