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Infect Immun. 2009 Nov;77(11):4690-5. doi: 10.1128/IAI.01515-08. Epub 2009 Aug 24.

Susceptibility to infectious diseases based on antimicrobial peptide production.

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1
Unidad de Investigación Médica-Zacatecas, IMSS, Interior de la Alameda #45, Zacatecas, Zacatecas, Mexico.

Abstract

In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.

PMID:
19703980
PMCID:
PMC2772553
DOI:
10.1128/IAI.01515-08
[Indexed for MEDLINE]
Free PMC Article
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