Format

Send to

Choose Destination
Cell. 2009 Aug 21;138(4):619-21. doi: 10.1016/j.cell.2009.08.010.

Only two ways to achieve perfection.

Author information

1
Department of Pharmacology, Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Abstract

The functional repertoire of a network is determined by its topology. Ma et al. (2009) analyze enzyme networks with three nodes and take a reverse-engineering approach to ask how many core network topologies can establish perfect adaptation, the ability to reset after perturbation. Surprisingly, the answer is just two.

PMID:
19703388
DOI:
10.1016/j.cell.2009.08.010
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center