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Graefes Arch Clin Exp Ophthalmol. 2010 Feb;248(2):161-6. doi: 10.1007/s00417-009-1175-6. Epub 2009 Aug 25.

Imaging of macroaneurysms occurring during retinal vein occlusion and diabetic retinopathy by indocyanine green angiography and high resolution optical coherence tomography.

Author information

1
Department of Ophthalmology of the Fondation Ophtalmologique Rothschild, Université Pierre et Marie Curie Paris6, 75019 Paris, France.

Abstract

BACKGROUND:

Macular edema occurring after retinal vein occlusion (RVO) or diabetic retinopathy (DR) may be due to the development of capillary and/or venous macroaneurysms (MAs). Here, we investigated the respective contribution of fluorescein angiography (FA), of indocyanine green angiography (ICGA) and of high-resolution optical coherence tomography (HR-OCT) to their detection.

METHODS:

Review of the charts of six consecutive patients with MAs secondary to RVO (n = 4) or DR (n = 2). For each patient, FA, ICGA and HR-OCT data were analyzed and compared.

RESULTS:

All detectable MAs were detected by ICGA, while in three eyes FA failed to show them. Overall, ICGA provided a better delineation of MAs than FA. In all cases, HR-OCT identified MAs under the form of a vascular structure with a reflective wall surrounding a lumen containing variably reflective material.

CONCLUSIONS:

MAs can develop during the course of RVO and DR. ICGA and HR-OCT improves the identification of capillary and venous MAs, and may thus be of interest to better identify sites of blood-retinal barrier rupture during chronic macular edema due to RVO or DR.

PMID:
19701812
DOI:
10.1007/s00417-009-1175-6
[Indexed for MEDLINE]

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