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Rev Med Chil. 2009 May;137(5):675-9. doi: /S0034-98872009000500012. Epub 2009 Jul 17.

[Limbic encephalitis associated to voltage dependent potassium channel antibodies: report of one case].

[Article in Spanish]

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Departamento de Neurología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.


Limbic encephalitis (LE) can be associated to cancer, viral infection or be idiopathic. One form is associated to voltage dependent potassium channel (VKC) antibodies. The clinical presentation includes impairment of consciousness, amnesia and temporal lobe seizures; typical abnormalities are also found in brain magnetic resonance. We report a 68 year-old male who had LE associated to VKC antibodies. The patient was treated with steroids with a partial response. At the moment of the report he is asymptomatic and continues with prednisone treatment .

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