Format

Send to

Choose Destination
Mol Gen Genet. 1990 Jan;220(2):334-8.

The fimD gene required for cell surface localization of Escherichia coli type 1 fimbriae.

Author information

1
Department of Microbiology, Technical University of Denmark, Lyngby.

Abstract

The fimD gene of Escherichia coli K12 was shown to be necessary for surface localization of type 1 fimbriae, since deletion of the gene resulted in a virtually bald phenotype. The FimD protein was found to be located in the outer membrane. Expressed alone, this protein had a very deleterious effect on cell growth. The DNA sequence of the fimD gene was determined; the corresponding amino acid sequence of the FimD protein was compared with those of the PapC and FaeD proteins. A deletion derivative of FimD gave clues as to which parts of the protein were necessary for outer membrane integration.

PMID:
1970114
DOI:
10.1007/bf00260505
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center