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Lancet. 1990 Apr 21;335(8695):939-40.

Hypothesis: does breast cancer originate in utero?

Author information

1
Department of Epidemiology, School of Public Health, Harvard University, Boston, Massachusetts 02115.

Abstract

Factors that increase the risk of cancer during adult life may also increase the risk of cancer when they act in utero (eg, ionising radiation and diethylstilboestrol in human beings and chemicals in animals). The existing empirical data seem to be compatible with the hypothesis that increased concentrations of oestrogens in pregnancy increase the probability of future occurrence of breast cancer in daughters.

PMID:
1970028
DOI:
10.1016/0140-6736(90)91000-z
[Indexed for MEDLINE]

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