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Immunity. 2009 Aug 21;31(2):174-6. doi: 10.1016/j.immuni.2009.08.002.

LAT polices T cell activation.

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1
Institute for Immunology and Infection Research, The University of Edinburgh, Edinburgh EH9 3JT, UK.

Abstract

Mutations in the adaptor molecule LAT can lead to autoimmunity. In this issue of Immunity, Mingueneau et al. (2009) describe how this may not be a failure of central tolerance.

PMID:
19699166
DOI:
10.1016/j.immuni.2009.08.002
[Indexed for MEDLINE]
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