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J Infect Dis. 1990 May;161(5):1016-9.

Abnormalities of T cell immunoregulation in hemorrhagic fever with renal syndrome.

Author information

1
Department of Infectious Diseases, Second Teaching Hospital, Fourth Military Medical University, Xian, People's Republic of China.

Abstract

The functions of spontaneous suppressor T cells and T lymphocyte subsets in patients with hemorrhagic fever with renal syndrome were compared. In the early stages of disease, decreased activity of spontaneous suppressor T cells was concurrent with increased numbers of CD8+ cells and a reversed CD4:CD8 ratio. These changes were related to abnormalities in serum C3 level and circulating immune complexes. In the recovery stages of the illness, spontaneous suppressor T cell activity and T cell subsets returned to normal levels.

PMID:
1969885
DOI:
10.1093/infdis/161.5.1016
[Indexed for MEDLINE]

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