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Muscle Nerve. 2009 Oct;40(4):626-8. doi: 10.1002/mus.21438.

Lyme disease serology in amyotrophic lateral sclerosis.

Author information

1
Neurology Clinical Trials Unit, Massachusetts General Hospital, Harvard Medical School, 13th Street, Building 149, Room 2274, Charlestown, Massachusetts 02129, USA. mqureshi@partners.org

Abstract

Lyme disease is sometimes part of the differential diagnosis for amyotrophic lateral sclerosis (ALS). Herein we report on 414 individuals with ALS at the Massachusetts General Hospital who underwent laboratory testing for Lyme disease. Twenty-four (5.8%) were seropositive, but only 4 (0.97%) had confirmed past immunoreactive infection. Two of these patients received ceftriaxone for 1 month without clinical improvement. Lyme disease was rare in 414 patients with ALS and is not likely to be causative.

PMID:
19697382
DOI:
10.1002/mus.21438
[Indexed for MEDLINE]

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