Angiosarcoma arising in mature cystic teratoma of the ovary: a case report and review of the literature

Int J Gynecol Pathol. 2009 Sep;28(5):453-7. doi: 10.1097/PGP.0b013e31819d4574.

Abstract

Mature cystic teratoma of the ovary is the most common ovarian tumor. Malignant transformation of this neoplasm is rare and is mostly represented by squamous carcinoma. Less frequently, malignant transformation is represented by a sarcoma. To date, only 5 cases of angiosarcoma arising in a mature cystic teratoma of the ovary have been reported. Herein, we report the clinicopathologic features of one such case. A review of the literature is also presented.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Combined Modality Therapy
  • Doxorubicin / administration & dosage
  • Fatal Outcome
  • Female
  • Gynecologic Surgical Procedures
  • Hemangiosarcoma / pathology*
  • Hemangiosarcoma / therapy
  • Humans
  • Ifosfamide / administration & dosage
  • Immunohistochemistry
  • Neoplasms, Multiple Primary / pathology*
  • Neoplasms, Multiple Primary / therapy
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / therapy
  • Teratoma / pathology*
  • Teratoma / therapy

Substances

  • Doxorubicin
  • Ifosfamide