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Surg Laparosc Endosc Percutan Tech. 2009 Aug;19(4):321-3. doi: 10.1097/SLE.0b013e3181b13933.

Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy.

Author information

1
Department of Anesthesiology, Istanbul University, Cerrahpasa Medical Faculty, Istanbul, Turkey.

Abstract

PURPOSE:

In this study, the effects of intravenous paracetamol treatment on early postoperative period analgesia and recovery characteristics after laparoscopic cholecystectomy have been evaluated.

METHODS:

Forty patients whose American Society of Anesthesiologists physical status I or II underwent laparoscopic cholecystectomy and randomly divided into 2 equal groups. In the first group, 1 g paracetamol was given to the patients intravenously after intubation before start of the surgery in 15 minutes. The 100 mL 0.9% NaCl was infused intravenously for the control group in 15 minutes. Postoperative pain was evaluated and recovery characteristics were evaluated.

RESULTS:

Verbal and visual pain scores of the paracetamol group were significantly lower than control group (P<0.05). First morphine requirement and total administered morphine dose and duration of staying in recovery room were significantly decreased in the paracetamol group (P<0.05).

CONCLUSIONS:

Beside its effective analgesic properties, paracetamol administration during per operative period supports effective and faster recovery.

PMID:
19692881
DOI:
10.1097/SLE.0b013e3181b13933
[Indexed for MEDLINE]

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