Format

Send to

Choose Destination
See comment in PubMed Commons below
Horm Res. 2009;72(2):82-7. doi: 10.1159/000232160. Epub 2009 Aug 18.

The interrelationships between abdominal adiposity, leptin and bone mineral content in overweight Latino children.

Author information

1
College of Health Sciences, TUI University, Cypress, Calif. 90630, USA. aafghani@tuiu.edu

Abstract

BACKGROUND/AIMS:

The link between abdominal fat and bone mineral content (BMC), independent of weight, has not been extensively studied. In Latino children, the contributions of abdominal subcutaneous and visceral fat to BMC have not been examined. Research on the effect of leptin on BMC has also been inconclusive.

METHODS:

The present study included 256 overweight Latino children (111 girls, 145 boys; mean BMI 28.2; age 11.1 +/- 1.7 years) from Los Angeles, California. Subcutaneous abdominal adipose tissue (SAAT) and intra-abdominal adipose tissue (IAAT) were determined by single-slice magnetic resonance imaging. BMC was measured using dual-energy X-ray absorptiometry.

RESULTS:

Independent of age, Tanner stage and weight, abdominal adipose tissue (SAAT + IAAT) was inversely correlated with BMC (r = -0.46, p < 0.0001; n = 256). In girls, there was an inverse correlation between SAAT and BMC (r = -0.38, p < 0.05), between IAAT and BMC (r = -0.32, p < 0.05) and between leptin and BMC (r = -0.39, p < 0.05). In boys, SAAT and BMC were inversely correlated (r = -0.26, p < 0.05), but the correlation between IAAT and BMC was not significant (p = 0.22). Leptin was also inversely correlated with BMC (r = -0.38, p < 0.05) in boys and contributed to the variances in BMC in both girls and boys.

CONCLUSION:

Total abdominal adipose fat and leptin are negatively associated with BMC in Latino children. The correlation between SAAT and BMC is stronger in girls than boys. IAAT and BMC are negatively associated in girls but not correlated in boys.

PMID:
19690425
PMCID:
PMC2790747
DOI:
10.1159/000232160
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for S. Karger AG, Basel, Switzerland Icon for PubMed Central
    Loading ...
    Support Center