Format

Send to

Choose Destination
Curr Protoc Protein Sci. 2009 Aug;Chapter 12:Unit 12.1 12.1.1-8. doi: 10.1002/0471140864.ps1201s57.

Overview of glycoconjugate analysis.

Author information

1
University of California San Diego, La Jolla, California, USA.

Abstract

Whereas DNA, RNA, and proteins are linear polymers that can usually be directly sequenced, glycans show substantially more complexity, having branching and anomeric configurations (alpha and beta linkages). The biosynthesis of glycans, termed glycosylation, is extremely complex, is not template-driven, varies among different cell types, and cannot be easily predicted from simple rules. This overview discusses the stereochemistry of monosaccharides and glycans and provides diagrammatic representations of monosaccharides (Fisher projections and Haworth representations) and formulas for representation of glycan chains. A glossary of terms used in glycobiology is also provided.

PMID:
19688734
PMCID:
PMC2749716
DOI:
10.1002/0471140864.ps1201s57
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center