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BMC Ophthalmol. 2009 Aug 17;9:7. doi: 10.1186/1471-2415-9-7.

Comparative efficacy of topical tetraVisc versus lidocaine gel in cataract surgery.

Author information

1
Department of Ophthalmology, University of Florida College of Medicine, Jacksonville, Florida, USA. kvchalam@aol.com

Abstract

BACKGROUND:

To compare the clinical efficacy of lidocaine 2% with tetracaine 0.5% for cataract surgery.

METHODS:

In a randomized, multi-surgeon, controlled clinical trial,122 consecutive cataract cases eligible for topical anesthesia, were randomly assigned to receive lidocaine 2% gel (1 ml) or tetracaine solution 0.5% (TetraVisc, 0.5 ml) before clear corneal phacoemulsification. Main outcome measure was visual analog scale (0 to 10), which was used to measure intra-operative pain. Secondary outcome measures included patients' discomfort due to tissue manipulation and surgeon graded patients' cooperation. Duration of surgery and intra-operative complications were also recorded.

RESULTS:

The mean age in TetraVisc (TV) group was 70.4 years and in the lidocaine gel group (LG) it was 70.6 years (p = 0.89). Patient reported mean intra-operative pain scores by visual analog scale were 0.70 +/- 0.31 in TV group and 1.8 +/- 0.4 in LG group (P < 0.001). Mean patient cooperation was also marginally better in the TV group (8.3 +/- 0.3) compared to LG group (8.4 +/- 0.6) (P = 0.25). 96% of patients in TV group showed intra-operative corneal clarity compared to 91% in LG group. TV group had less (1 out of 61 patients, 1.6%) intra-operative complications than LG group (3 out of 61 patients, 4.8%). No anesthesia related complications were noted in either group

CONCLUSION:

Topical TetraVisc solution was superior to lidocaine 2% gel for pain control in patients undergoing clear corneal phacoemulsification. Lidocaine 2% gel is similar to TetraVisc in patient comfort and surgeon satisfaction.

TRIAL REGISTRATION:

Clinical trials number: ISRCTN78374774.

PMID:
19686592
PMCID:
PMC2736919
DOI:
10.1186/1471-2415-9-7
[Indexed for MEDLINE]
Free PMC Article

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