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Pediatr Dermatol. 2010 Mar-Apr;27(2):192-4. doi: 10.1111/j.1525-1470.2009.00942.x. Epub 2009 Jul 20.

Disseminated varicella zoster virus in an immunized child as the acquired immunodeficiency syndrome-defining illness.

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Department of Medicine, Cuyahoga Falls General Hospital, Cuyahoga Falls, Ohio, USA.


Varicella zoster virus (VZV) immunization aids in the prevention of future VZV infections in immunocompetent patients; however, severely immunocompromised patients remain at increased risk of VZV infection. We report a case of a 10-year-old boy previously immunized to Varicella who presented with herpes zoster with hematogenous dissemination as the Acquired Immunodeficiency Syndrome-defining illness. Disseminated VZV is more commonly seen in human immunodeficiency virus (HIV)-infected individuals with more advanced disease, as was the case with our patient. Disseminated VZV infection in a previously immunized child should raise suspicion for underlying immunosuppression.

[Indexed for MEDLINE]

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