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Lancet. 1990 Mar 10;335(8689):579-82.

Night-time nasal ventilation in neuromuscular disease.

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Department of Paediatrics, Hammersmith Hospital, London.


14 patients, aged 2-28 years, with neuromuscular disorders and symptomatic sleep hypoventilation received night-time intermittent positive-pressure ventilation with a nasal mask. 9 were treated de novo and 5 had previously been maintained on a cuirass or iron lung. Nasal ventilation was very effective in 10 patients but was not tolerated in 4 of the 5 youngest patients. Nasal ventilation was preferable to other methods of ventilation because the system was non-invasive, quiet, portable, and easy to use and because it allowed considerable independence.

[Indexed for MEDLINE]

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