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Methods Mol Biol. 2009;574:63-74. doi: 10.1007/978-1-60327-321-3_6.

Imaging vasculature and lymphatic flow in mice using quantum dots.

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1
Molecular Biosensor and Imaging Center, Carnegie Mellon University, Pittsburgh, PA, USA.

Abstract

Quantum dots are ideal probes for fluorescent imaging of vascular and lymphatic tissues. On injection into appropriate sites, red- and near-infrared-emitting quantum dots provide excellent definition of vasculature, lymphoid organs, and lymph nodes draining both normal tissues and tumors. We detail methods for use with commercially available quantum dots and discuss common difficulties.

PMID:
19685300
DOI:
10.1007/978-1-60327-321-3_6
[Indexed for MEDLINE]
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