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Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Jun;26(6):814-20. doi: 10.1080/02652030902729908.

Evaluation of the illegal use of clenbuterol in Portuguese cattle farms from drinking water, urine, hair and feed samples.

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Grupo de Bromatologia, Centro de Estudos Farmaceuticos, Faculdade de Farmacia da Universidade de Coimbra, 3000-295 Coimbra, Portugal.


The recent discovery of clenbuterol contamination in Portuguese food led to the specific inspection of 16 cattle farms for beta-agonists, involving the analysis of a total of 486 samples (78 feed, 106 drinking water, 168 urine and 134 hair). The samples were screened for the beta-agonists: bromobuterol, cimaterol, clenbuterol, clenpenterol, clenproperol, hydroxymethylclenbuterol, mapenterol, salbutamol and terbutaline. Only clenbuterol was found in all analyzed matrices and the most likely method of illegal administration to animals was through drinking water. Of all samples analysed, 14.15% of drinking water were found positive in the range 0.03-3.80 mg l(-1) clenbuterol. Inclusion of hair samples in the Portuguese plan for clenbuterol residue control in live animals is discussed.

[Indexed for MEDLINE]

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