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Ann Nucl Med. 2009 Sep;23(7):671-6. doi: 10.1007/s12149-009-0292-y. Epub 2009 Aug 13.

Diagnostic usefulness of 18F-FDG PET/CT in the differentiation of pulmonary artery sarcoma and pulmonary embolism.

Author information

1
Department of Nuclear Medicine, Saitama Medical University International Medical Center, Hidaka, Saitama 350-1298, Japan. itoukimiteru@yahoo.co.jp

Abstract

OBJECTIVE:

The purpose of this study was to evaluate the usefulness of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in differentiating pulmonary artery sarcoma from pulmonary embolism.

MATERIALS AND METHODS:

We evaluated three patients with pulmonary artery sarcoma and 10 patients with proximal pulmonary embolism (6 men and 7 women, ranging in age from 35 to 94 years). All the patients had evidence of perfusion defects in their proximal pulmonary arteries on contrast-enhanced computed tomography (CT) scans performed prior to PET/CT. The maximum standardized uptake value (SUV(max)) of FDG uptake in all the lesions was measured using PET/CT. The location of lesions, background uptake or thrombi in the legs were evaluated in both groups as basic characteristics.

RESULTS:

The mean SUV(max) of the pulmonary artery sarcomas (7.63 +/- 2.21, n = 3) and the pulmonary embolisms (2.31 +/- 0.41, n = 10) were significantly different (P < 0.05). The mean times between the initial contrast-enhanced CT scan and PET/CT scan were similar in both groups (P = 0.7804). The differences in the locations in lesions between the three groups (right, left and bilateral) or background uptakes were not significant.

CONCLUSION:

FDG PET/CT could distinguish pulmonary artery sarcoma from pulmonary embolism based on the SUV(max) value.

PMID:
19680740
DOI:
10.1007/s12149-009-0292-y
[Indexed for MEDLINE]

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