Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Rev Neurosci. 2009 Sep;10(9):659-69. doi: 10.1038/nrn2667. Epub 2009 Aug 12.

Is the rostro-caudal axis of the frontal lobe hierarchical?

Author information

1
Department of Cognitive & Linguistic Sciences, Brown University, Providence, Rhode Island 02912, USA. David_Badre@brown.edu

Abstract

The frontal lobes in the brain are a component of the cerebral system that supports goal-directed behaviour. However, their functional organization remains controversial. Recent studies have reported rostro-caudal distinctions in frontal cortex activity based on the abstractness of action representations. In addition, some have proposed that these differences reflect a hierarchical organization, whereby anterior frontal regions influence processing by posterior frontal regions during the realization of abstract action goals as motor acts. However, few have considered whether the anatomy and physiology of the frontal lobes support such a scheme. To address this gap, this Review surveys anatomical, neuroimaging, electrophysiological and developmental findings, and considers the question: could the organization of the frontal cortex be hierarchical?

Comment in

PMID:
19672274
PMCID:
PMC3258028
DOI:
10.1038/nrn2667
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Support Center