[Application of aptamers to medicine: pharmacological profile and results of clinical trials on pegaptanib sodium (Macugen) for age-related macular degeneration]

Nihon Yakurigaku Zasshi. 2009 Aug;134(2):87-95. doi: 10.1254/fpj.134.87.
[Article in Japanese]
No abstract available

MeSH terms

  • Animals
  • Aptamers, Nucleotide / pharmacokinetics
  • Aptamers, Nucleotide / pharmacology*
  • Aptamers, Nucleotide / therapeutic use*
  • Humans
  • Macular Degeneration / drug therapy*
  • Mice
  • Receptors, Vascular Endothelial Growth Factor / drug effects
  • Vascular Endothelial Growth Factor A / antagonists & inhibitors*

Substances

  • Aptamers, Nucleotide
  • Vascular Endothelial Growth Factor A
  • pegaptanib
  • Receptors, Vascular Endothelial Growth Factor