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Lupus. 2009 Sep;18(10):920-3. doi: 10.1177/0961203309106920.

Antiphosphatidylethanolamine antibodies and the antiphospholipid syndrome.

Author information

1
Laboratoire d'Immunologie, Hôpital de La Conception, Marseille, France. msanmarco@ap-hm.fr

Abstract

The antiphospholipid antibodies included as laboratory criteria of the antiphospholipid syndrome (APS) are antibodies reacting with anionic phospholipids - anticardiolipin antibodies and lupus anticoagulant - and with beta(2)-glycoprotein I. However, antibodies reacting with phosphatidylethanolamine (aPE), a zwitterionic phospholipid, have also been described to be associated with the main features of APS. The objectives of this review are to describe the characteristics of aPE and to bring attention to recent evidence that aPE are correlated with the main clinical features of APS, notably, in the absence of the laboratory criteria of this syndrome.

PMID:
19671793
DOI:
10.1177/0961203309106920
[Indexed for MEDLINE]

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