Format

Send to

Choose Destination
See comment in PubMed Commons below
J Biol. 2009;8(7):62. doi: 10.1186/jbiol166. Epub 2009 Aug 5.

Parasite immunomodulation and polymorphisms of the immune system.

Author information

1
Centre for Immunity, Infection and Evolution, and Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, EH9 3JT, UK. rick.maizels@ed.ac.uk

Abstract

Parasites are accomplished evaders of host immunity. Their evasion strategies have shaped every facet of the immune system, driving diversity within gene families and immune gene polymorphisms within populations. New studies published recently in BMC Biology and Journal of Experimental Medicine document parasite-associated immunosuppression in natural populations and suggest that host genetic variants favoring resistance to parasites may be detrimental in the absence of infection.

PMID:
19664200
PMCID:
PMC2736671
DOI:
10.1186/jbiol166
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for BioMed Central Icon for PubMed Central
    Loading ...
    Support Center