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Biosci Biotechnol Biochem. 2009 Aug;73(8):1866-8. Epub 2009 Aug 7.

Effects of Psilocybe argentipes on marble-burying behavior in mice.

Author information

1
Department of Health and Nutrition, Takasaki University of Health and Welfare, Gunma, Japan.

Abstract

Psilocybe argentipes is a hallucinogenic mushroom. The present study examined the effects of P. argentipes on marble-burying behavior, which is considered an animal model of obsessive-compulsive disorder. P. argentipes significantly inhibited marble-burying behavior without affecting locomotor activity as compared with the same dose of authentic psilocybin. These findings suggest that P. argentipes would be efficient in clinical obsessive-compulsive disorder therapy.

PMID:
19661714
DOI:
10.1271/bbb.90095
[Indexed for MEDLINE]
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